Archive: Story

• Jeanne Mandelblatt, MD, MPH among 2023 NCI Outstanding Investigator Award Recipients

  NCI’s Outstanding Investigator Award supports accomplished leaders in cancer research, who are providing significant contributions toward understanding cancer and developing applications that may lead to a breakthrough in biomedical, behavioral, or clinical cancer research. Below are profiles of the most recent NCI Outstanding Investigator Award recipients.

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• Knitting Together Aging and Cancer

  Jeanne Mandelblatt is good at bringing things together, whether it’s coalescing disparate data to better understand how screening impacts cancer outcomes or threads of colorful yarn for a new knitted blanket.

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• Novel Research Shows Older Breast Cancer Survivors Experience Accelerated Aging, Worse Functional Outcomes

  In a new multicenter study, researchers from Georgetown University’s Lombardi Comprehensive Cancer Center, the Medical College of Wisconsin (MCW), UCLA and several other leading cancer centers from across the nation examined whether cancer and its treatments accelerate aging. Using novel epigenetic measures to assess biological aging, investigators found that older breast cancer survivors — particularly those exposed to chemotherapy — showed greater epigenetic aging than their same-aged peers without cancer, which may relate to worse outcomes.

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• Long-term Study Supports Link Between Inflammation and Cognitive Problems in Older Breast Cancer Survivors

  Scientists are still trying to understand why many breast cancer survivors experience troubling cognitive problems for years after treatment. Inflammation is one possible culprit. A new long-term study of older breast cancer survivors, published today in the Journal of Clinical Oncology, adds important evidence to that potential link.

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• Jeanne Mandelblatt, MD, MPH appointed as the Ewing Chair

  Dear Members of the Lombardi Community, I am delighted to announce the appointment of Jeanne Mandelblatt, MD, MPH as the Frank M. Ewing Foundation Endowed Chair. Established in 2018, the Ewing Cha

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• Study Shows Sleep Disturbances During the Pandemic Were Similar between Breast Cancer Survivors and Healthy Controls

  Results from the Thinking and Living with Cancer Study (TLC) showed that the development of sleep disturbances during the early months of the COVID-19 pandemic increased symptoms of depression and anxiety among older women, but the findings did not differ between women who survived breast cancer and women without cancer. It is the first study to assess sleep disturbances and mental health outcomes among cancer survivors during the pandemic.

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• News 4 Your Sunday: Walk for Breast Cancer

  News4’s Pat Lawson Muse talks with Dr. Jeanne Mandelblatt of Georgetown Lombardi Institute for Cancer & Aging.

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• Reducing your risk of cognitive disease: A $12M research study, 60 years in the making

  A McCourt researcher has dedicated her career to aging research and a decades-old study, revealing a non-medical intervention that proves resilient against dementia.

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• Vascular Defects Appear to Underlie the Progression of Parkinson’s Disease

  In an unexpected discovery, Georgetown University Medical Center researchers have identified what appears to be a significant vascular defect in patients with moderately severe Parkinson’s disease. The finding could help explain an earlier outcome of the same study, in which the drug nilotinib was able to halt motor and nonmotor (cognition and quality of life) decline in the long term.

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• Renowned Georgetown Cancer and Aging Researcher Receives Top Honor in Her Field

  When Jeanne Mandelblatt, MD, PhD, MPH, reflects on the arc of her research career, she sees no single standout moment that cemented her path. Instead, the revered member of Georgetown Lombardi Comprehensive Cancer Center and professor of oncology and medicine at Georgetown attributes her distinguished career to a continuum of work “based on persistence, curiosity and serendipity,” coupled with work involving wonderful transdisciplinary teams of colleagues.

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